nlmixr

This package has been dropped from support on MPN. The last snapshot it was available in is 2022-10-20

Nonlinear Mixed Effects Models in Population Pharmacokinetics and Pharmacodynamics

Fit and compare nonlinear mixed-effects models in differential equations with flexible dosing information commonly seen in pharmacokinetics and pharmacodynamics (Almquist, Leander, and Jirstrand 2015 <doi:10.1007/s10928-015-9409-1>). Differential equation solving is by compiled C code provided in the 'RxODE' package (Wang, Hallow, and James 2015 <doi:10.1002/psp4.12052>).

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This version of nlmixr can be found in the following snapshots:

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Imports/Depends/LinkingTo/Enhances (22)
R Rcpp >= 0.12.3 brew lbfgsb3c dparser ggplot2 rex minqa n1qn1 >= 6.0.1-10 fastGHQuad RxODE >= 1.1.5 magrittr backports symengine dparser >= 0.1.8 RxODE >= 1.0.0-0 RcppEigen >= 0.3.3.3.0 lbfgsb3c Rcpp BH StanHeaders >= 2.18.0 RcppArmadillo >= 0.5.600.2.0

Suggests (40)
Deriv Rvmmin broom.mixed crayon knitr data.table devtools digest dotwhisker dplyr expm flextable ggtext patchwork gridExtra huxtable lbfgs lotri madness matrixcalc nloptr officer pkgdown reshape2 rmarkdown testthat tidyr ucminf vpc >= 1.1.0 xgxr yaml xpose generics tibble checkmate cli qs covr forecast latticeExtra

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nlmixr

Nonlinear Mixed Effects Models in Population Pharmacokinetics and Pharmacodynamics

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