qpNCA

Noncompartmental Pharmacokinetic Analysis by qPharmetra

Computes noncompartmental pharmacokinetic parameters for drug concentration profiles. For each profile, data imputations and adjustments are made as necessary and basic parameters are estimated. Supports single dose, multi-dose, and multi-subject data. Supports steady-state calculations and various routes of drug administration. See ?qpNCA and vignettes. Methodology follows Rowland and Tozer (2011, ISBN:978-0-683-07404-8), Gabrielsson and Weiner (1997, ISBN:978-91-9765-100-4), and Gibaldi and Perrier (1982, ISBN:978-0824710422).

Tests Vignettes

Available Snapshots

This version of qpNCA can be found in the following snapshots:

Dependencies

Imports/Depends/LinkingTo/Enhances (6)
  • R
  • dplyr >= 0.7.0
  • tidyr >= 0.8.2
  • magrittr
  • ggplot2
  • knitr
  • Suggests (4)
  • rmarkdown
  • markdown
  • covr
  • testthat >= 2.1.0
  • Version History