This function will set the default PKNCA options. If given no
inputs, it will provide the current option set. If given name/value
pairs, it will set the option (as in the options
function). If given a name, it will return the value for the
parameter. If given the default option as true, it will
provide the default options.
PKNCA.options(..., default = FALSE, check = FALSE, name, value)
| ... | options to set or get the value for |
|---|---|
| default | (re)sets all default options |
| check | check a single option given, but do not set it (for validation of the values when used in another function) |
| name | An option name to use with the |
| value | An option value (paired with the |
If...
returns the current options.
returns NULL
the current value of that option is returned as a scalar
the current values of those options are returned as a list
Options are either for calculation or summary functions. Calculation
options are required for a calculation function to report a result
(otherwise the reported value will be NA). Summary options are
used during summarization and are used for assessing what values are
included in the summary.
See the vignette 'Options for Controlling PKNCA' for a current list of options.
Other PKNCA calculation and summary settings:
PKNCA.choose.option(),
PKNCA.set.summary()
PKNCA.options()#> $adj.r.squared.factor #> [1] 1e-04 #> #> $max.missing #> [1] 0.5 #> #> $auc.method #> [1] "lin up/log down" #> #> $conc.na #> [1] "drop" #> #> $conc.blq #> $conc.blq$first #> [1] "keep" #> #> $conc.blq$middle #> [1] "drop" #> #> $conc.blq$last #> [1] "keep" #> #> #> $first.tmax #> [1] TRUE #> #> $allow.tmax.in.half.life #> [1] FALSE #> #> $min.hl.points #> [1] 3 #> #> $min.span.ratio #> [1] 2 #> #> $max.aucinf.pext #> [1] 20 #> #> $min.hl.r.squared #> [1] 0.9 #> #> $tau.choices #> [1] NA #> #> $single.dose.aucs #> start end auclast aucall aumclast aumcall aucint.last aucint.last.dose #> 1 0 24 TRUE FALSE FALSE FALSE FALSE FALSE #> 2 0 Inf FALSE FALSE FALSE FALSE FALSE FALSE #> aucint.all aucint.all.dose auclast.dn aucall.dn aumclast.dn aumcall.dn cmax #> 1 FALSE FALSE FALSE FALSE FALSE FALSE FALSE #> 2 FALSE FALSE FALSE FALSE FALSE FALSE TRUE #> cmin tmax tlast tfirst clast.obs cl.last cl.all f mrt.last mrt.iv.last #> 1 FALSE FALSE FALSE FALSE FALSE FALSE FALSE FALSE FALSE FALSE #> 2 FALSE TRUE FALSE FALSE FALSE FALSE FALSE FALSE FALSE FALSE #> vss.last vss.iv.last cav ctrough ptr tlag deg.fluc swing ceoi ae #> 1 FALSE FALSE FALSE FALSE FALSE FALSE FALSE FALSE FALSE FALSE #> 2 FALSE FALSE FALSE FALSE FALSE FALSE FALSE FALSE FALSE FALSE #> clr.last clr.obs clr.pred fe half.life r.squared adj.r.squared lambda.z #> 1 FALSE FALSE FALSE FALSE FALSE FALSE FALSE FALSE #> 2 FALSE FALSE FALSE FALSE TRUE FALSE FALSE FALSE #> lambda.z.time.first lambda.z.n.points clast.pred span.ratio cmax.dn cmin.dn #> 1 FALSE FALSE FALSE FALSE FALSE FALSE #> 2 FALSE FALSE FALSE FALSE FALSE FALSE #> clast.obs.dn clast.pred.dn cav.dn ctrough.dn thalf.eff.last thalf.eff.iv.last #> 1 FALSE FALSE FALSE FALSE FALSE FALSE #> 2 FALSE FALSE FALSE FALSE FALSE FALSE #> kel.last kel.iv.last aucinf.obs aucinf.pred aumcinf.obs aumcinf.pred #> 1 FALSE FALSE FALSE FALSE FALSE FALSE #> 2 FALSE FALSE TRUE FALSE FALSE FALSE #> aucint.inf.obs aucint.inf.obs.dose aucint.inf.pred aucint.inf.pred.dose #> 1 FALSE FALSE FALSE FALSE #> 2 FALSE FALSE FALSE FALSE #> aucinf.obs.dn aucinf.pred.dn aumcinf.obs.dn aumcinf.pred.dn aucpext.obs #> 1 FALSE FALSE FALSE FALSE FALSE #> 2 FALSE FALSE FALSE FALSE FALSE #> aucpext.pred cl.obs cl.pred mrt.obs mrt.pred mrt.iv.obs mrt.iv.pred #> 1 FALSE FALSE FALSE FALSE FALSE FALSE FALSE #> 2 FALSE FALSE FALSE FALSE FALSE FALSE FALSE #> mrt.md.obs mrt.md.pred vz.obs vz.pred vss.obs vss.pred vss.iv.obs vss.iv.pred #> 1 FALSE FALSE FALSE FALSE FALSE FALSE FALSE FALSE #> 2 FALSE FALSE FALSE FALSE FALSE FALSE FALSE FALSE #> vss.md.obs vss.md.pred vd.obs vd.pred thalf.eff.obs thalf.eff.pred #> 1 FALSE FALSE FALSE FALSE FALSE FALSE #> 2 FALSE FALSE FALSE FALSE FALSE FALSE #> thalf.eff.iv.obs thalf.eff.iv.pred kel.obs kel.pred kel.iv.obs kel.iv.pred #> 1 FALSE FALSE FALSE FALSE FALSE FALSE #> 2 FALSE FALSE FALSE FALSE FALSE FALSE #>PKNCA.options(default=TRUE) PKNCA.options("auc.method")#> [1] "lin up/log down"PKNCA.options(name="auc.method")#> [1] "lin up/log down"PKNCA.options(auc.method="lin up/log down", min.hl.points=3)