R/pk.calc.simple.R
pk.calc.vd.RdCalculate the volume of distribution (Vd) or observed volume of distribution (Vd/F)
pk.calc.vd(dose, aucinf, lambda.z)
| dose | One or more doses given during an interval |
|---|---|
| aucinf | Area under the curve to infinity (either predicted or observed). |
| lambda.z | Elimination rate constant |
The observed volume of distribution
vd is dose/(aucinf * lambda.z).
If dose is the same length as the other inputs, then
the output will be the same length as all of the inputs; the
function assumes that you are calculating for multiple intervals
simultaneously. If the inputs other than dose are scalars
and dose is a vector, then the function assumes multiple
doses were given in a single interval, and the sum of the
doses will be used for the calculation.