Calculate the mean residence time (MRT) for single-dose data or linear multiple-dose data.

pk.calc.mrt(auc, aumc)

pk.calc.mrt.iv(auc, aumc, duration.dose)

Arguments

auc	the AUC from 0 to infinity or 0 to tau
aumc	the AUMC from 0 to infinity or 0 to tau
duration.dose	The duration of the dose (usually an infusion duration for an IV infusion)

the numeric value of the mean residence time

mrt is aumc/auc - duration.dose/2 where duration.dose = 0 for oral administration.