Interpolation is performed aligning with PKNCA.options("auc.method"). Extrapolation outside of the measured times is not yet implemented.

pk.calc.time_above(
  conc,
  time,
  conc_above,
  method,
  options = list(),
  check = TRUE
)

Arguments

conc

Concentration measured

time

Time of concentration measurement (must be monotonically increasing and the same length as the concentration data)

conc_above

The concentration to be above (if missing will use PKNCA.choose.option(name="conc_above", value=conc_above, options=options))

method

The method for integration (either 'lin up/log down' or 'linear')

options

List of changes to the default PKNCA.options for calculations.

check

Run check.conc.time, clean.conc.blq, and clean.conc.na?

Value

the time above the given concentration