Parse PKMODEL BLOCK data
PKMODEL( ncmt = 1, depot = FALSE, cmt = NULL, trans = pick_trans(ncmt, depot), env = list(), pos = 1, ... )
| ncmt | number of compartments; must be 1 (one-compartment, not including a depot dosing compartment) or 2 (two-compartment model, not including a depot dosing compartment) |
|---|---|
| depot | logical indicating whether to add depot compartment |
| cmt | compartment names as comma-delimited character |
| trans | the parameterization for the PK model; must be 1, 2, 4, or 11 |
| env | parse environment |
| pos | block position number |
| ... | not used |
When using $PKMODEL, certain symbols must be defined in the
model specification depending on the value of ncmt, depot
and trans.
ncmt 1, depot FALSE, trans 2: CL, V
ncmt 1, depot TRUE , trans 2: CL, V,
KA
ncmt 2, depot FALSE, trans 4: CL, V1,
Q, V2
ncmt 2, depot TRUE , trans 4: CL, V2,
Q, V3, KA
If trans=11 is specified, use the symbols listed above for the
ncmt / depot combination, but append i at the end
(e.g. CLi or Qi or KAi).
If trans=1, the user must utilize the following symbols:
pred_CL for clearance
pred_V or pred_V2 for central compartment volume of
distribution
pred_Q for intercompartmental clearance
pred_V3 for for peripheral compartment volume of distribution
pred_KA for absorption rate constant