DoseFinding

Planning and Analyzing Dose Finding Experiments

The DoseFinding package provides functions for the design and analysis of dose-finding experiments (with focus on pharmaceutical Phase II clinical trials). It provides functions for: multiple contrast tests, fitting non-linear dose-response models (using Bayesian and non-Bayesian estimation), calculating optimal designs and an implementation of the MCPMod methodology.

Tests Vignettes

Available Snapshots

This version of DoseFinding can be found in the following snapshots:

Dependencies

Imports/Depends/LinkingTo/Enhances (2)
  • ggplot2
  • mvtnorm
  • Suggests (8)
  • numDeriv
  • Rsolnp
  • quadprog
  • multcomp
  • knitr
  • rmarkdown
  • testthat
  • RBesT
  • Version History