All functions |
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Functions to parse code blocks |
Parse PKMODEL BLOCK data |
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Request simulated output |
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About the lsoda differential equation solver used by mrgsolve |
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Coerce an object to class ev |
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Coerce a model object to list |
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Coerce an mrgsims object to list |
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Create a simulation data set from ev objects |
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Create a list of designs from a data frame |
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Return the code blocks from a model specification file |
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Select items to carry into simulated output |
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Get the compartment number from a compartment name |
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Extract the code from a model |
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Collapse OMEGA or SIGMA matrix lists |
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Collapse the matrices of a matlist object |
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Select and modify a data set for simulation |
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Set observation designs for the simulation |
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Extract model details |
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Re-evaluate the code in the ENV block |
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Return model environment |
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List objects in the model environment |
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Update objects in model environment |
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Event objects for simulating PK and other interventions |
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Replicate a list of events into a data set |
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Schedule dosing events on days of the week |
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dplyr verbs for event objects |
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Select columns from an ev object |
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Replicate an event object |
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Repeat a block of dosing events |
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Create intervention objects from Rx input |
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Schedule a series of event objects |
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Example input data sets |
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Create template data sets for simulation |
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Insert observations into a data set |
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Select and modify a idata set for simulation |
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Methods for working with the model compartment list |
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Check whether all required parameters needed in a model are present in an object |
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Check if an object is a model object |
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Check if an object is mrgsim output |
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Convert select upper case column names to lower case |
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Load the model shared object |
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Operations with matlist objects |
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Coerce R objects to block or diagonal matrices |
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Create matrices from vector input |
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Set RNG to use L'Ecuyer-CMRG |
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Write, compile, and load model code |
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Internal model library |
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modlib: PK/PD Model parameters, compartments, and output variables |
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modlib: Pharmacokinetic models |
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modlib: Pharmacokinetic / pharmacodynamic models |
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modlib: Target mediated disposition model |
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modlib: HCV viral dynamics models |
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Read a model specification file |
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Select parameter values from a model object |
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Simulate from a model object |
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Simulate from a model object with quicker turnaround |
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mrgsim variant functions |
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Methods for handling output with dplyr verbs |
Methods for modifying mrgsims objects |
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mrgsolve |
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Get all names from a model object |
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Import model estimates from a NONMEM ext file |
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Import model estimates from a NONMEM xml file |
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Prepare data.frame for input to mrgsim |
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Augment observations in the simulated output |
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Collect only observations in the simulated output |
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Manipulate OMEGA matrices |
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Show names of current output variables |
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Create and work with parameter objects |
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Plot method for mrgsims objects |
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Generate a quick plot of simulated data |
Plot data as an mrgsims object |
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Basic, simple simulation from model object |
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Extract estimates from NONMEM ext file |
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Make addl doses explicit in an event object or data set |
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Render a model to a document |
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Reserved words |
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Get model random effect variances and covariances |
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Print model code to the console |
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Manipulate SIGMA matrices |
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Access or clear arguments for calls to mrgsim |
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Return the location of the model shared object |
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Optional inputs for lsoda |
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Print summary of a mrgmod object |
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Operations with tgrid objects |
Re-scale time in the simulated output |
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Update the model object |
Validate and prepare a data sets for simulation |
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Validate and prepare idata data sets for simulation |
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Update parameters, initials, and settings within a model object |
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Zero out random effects in a model object |